Tonight's lineups

For the Orioles:
Lou Montanez LF
Adam Jones CF
Nick Markakis RF
Miguel Tejada 3B
Ty Wigginton 2B
Matt Wieters C
Nolan Reimold DH
Garrett Atkins 1B
Cesar Izturis SS

Jeremy Guthrie RHP

For the Red Sox:
Marco Scutaro SS
JD Drew RF
Dustin Pedroia 2B
Kevin Youkilis 1B
Victor Martinez C
David Ortiz DH
Adrian Beltre 3B
Jeremy Hermida LF
Josh Reddick CF

Jon Lester LHP

Guthrie has faced Matt Garza twice and Justin Duchscherer once in his first three starts, and he'll face Lester tonight and most likely CC Sabathia on Wednesday. In 39 career starts against the Orioles, those four pitchers are a combined 29-2 with a 2.40 ERA.

Guthrie hasn't allowed a first inning run in three starts this year after allowing 29 runs in the first inning last season.

Since B.J. Ryan allowed a three-run walk-off homer to David Ortiz on June 2, 2005, the Orioles are 8-32 at Fenway Park and have lost 13 of their last 14 games in Boston.

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