Unlucky seven: The seven runs the Orioles scored was their most since a 13-7 loss to Texas on May 20. They had scored just 14 runs over their previous nine games.
They are now 1-3 on a nine-game homestand, 4-18 over the last 22 games, 7-24 vs. the AL East and 16-42 on the season.
Is this good?: The Orioles are 1-9 this year versus New York with nine losses in a row. The Yankees have won 20 of the last 23 and 29 of the last 35 games between the teams.
New York is 10-4 over its last 14 games.
Losing pitcher Kevin Millwood gave up six runs and ten hits over 5 2/3 to fall to 0-7, 4.64.
Millwood on his night: "It seemed like we were swinging the bats well today and hitting some balls hard. I figured if I could keep them right there (when down 2-0) we had a chance. Did pretty much what I wanted to do in the third inning, but didn't make a pitch to Granderson and that turned the game around."
Granderson hit a 2-2 pitch for his second career Grand Slam and a 6-0 Yankees lead in the third. His other came on April 4, 2007 vs. Toronto while with Detroit.
Millwood on his ERA of 8.31 over his last three starts: "Just not throwing the ball where I want to enough. I need to locate to pitch well and with five walks I'm not locating where I need to be and even some of the balls they hit were located in bad spots. Simply, it's throwing the ball where I need to more often.
"I had plenty of runs today. I just didn't make the pitches, it's as simple as that."
Millwood leads the AL with 16 homers allowed.
Nick Swisher hit a two-run homer and matched his career-high with 5 RBI, the most by any player vs. the Orioles this year. He is batting .405-2-12 in ten games vs. the O's in 2010.
Breaking out?: After going 1 for 21 over his last six games, Matt Wieters went 3 for 5 with three singles and an RBI. Wieters has just 4 RBI over the past 25 games. This was Wieters first three-hit game of the year and first multi-hit game since May 27.
Adam ball: Adam Jones entered with just one RBI over his last 11 games, but hit a two-run homer in the eighth. It was his 7th of the season and went 399 feet to right center field.
Jones said this about Phil Hughes: "We're going to face him a lot. Thing is we had a lot of hits, but most were scattered off of him. We need to put more hits together, mix in an extra-base hit to clear the bases."
Miguel Tejada was 3 for 5 after going 6 for 34 over his previous eight games. Tejada has not homered over his last 142 at bats, the second longest stretch of his career.
Wednesday night here, it's Chris Tillman (0-1, 7.71) vs. CC Sabathia (5-3, 4.14). Sabathia is 12-1, 2.60 in 17 career starts vs. Baltimore.