RHP Jeremy Guthrie (7-10, 5.37) tonight will make his 22nd start of this season, his 11th on the road and the 3rd of his career vs. Detroit. Guthrie has lost his last two starts, both vs. Boston. He is 0-2, 7.43 in those outings. In the start before that, on July 19th at Chicago, he held the White Sox to just three hits in eight innings as he picked up his 7th win. Guthrie has allowed an American League-leading 26 homers and with 10 losses, he is tied for the league lead. AL Leaders, home runs allowed, 2009: 26 - Jeremy Guthrie, O's 23 - Trevor Cahill, Oak 22 - Joe Saunders, LAA 20 - Scott Baker, Minn 20 - Armando Galarraga, Det Right-handed batters hit .262 off Guthrie and lefties bat .279. The Orioles are 8-13 in his 21 starts. In five July starts, Guthrie went 1-3, 6.16. In ten road starts, he is 3-5, 6.39. Guthrie vs. Detroit: 2009: 0-0, 4.50, one start (6IP, 7H, 3R-ER, 1B, 10K) 2008: 1-0, 6.00, one start Career: 1-0, 4.74, five games, two starts (19IP, 24H, 5B, 19K) RHP Edwin Jackson (7-5, 2.64) tonight makes his 22nd start of 2009, his 10th at home and his 2nd of this year vs. the Birds. Jackson has been one of the AL's best pitchers this season and is second in the league in ERA. He has allowed 3ER or less in 15 straight starts. Jackson, 2009 ERA by month: April: 2.25 May: 2.34 June: 2.91 July: 3.16 Both right and left-handed hitters bat .223 off Jackson and he yields an average of just .163 when pitching with runners in scoring position. Despite his stellar pitching, Jackson has won just one of his last nine starts and the Tigers are only 11-10 in his 21 starts. In nine home starts, he is 4-1, 2.86. Jackson vs. Baltimore: 2009: 1-0, 0.00, one start (8IP, 2H, 0R, 1B, 7K) 2008: 2-0, 7.84, two starts Career: 3-1, 5.68, six games, four starts (25 1/3IP, 26H, 13B, 15K) Jackson was a 3-0 winner over the O's at Camden Yards on May 31st. He had a dominant outing, allowing just two hits over eight scoreless innings. Ty Wigginton doubled in the 8th and was the only Oriole to reach second base against him. Jackson threw 101 pitches that night.