Villar is batting second behind Peterson.
Mancini is batting cleanup ahead of Davis, who struck out three times in Game 1.
Cedric Mullins has moved up to seventh in the order after batting ninth last night and eighth earlier today.
Joey Rickard is starting in left field.
Yefry Ramírez is making his eighth major league start. He debuted against the Red Sox on June 13 and allowed three runs with six strikeouts in 4 1/3 innings, and he faced them on July 24 and allowed three runs with six strikeouts in five innings.
J.D. Martinez, Blake Swihart and Mookie Betts homered off him in the rematch. Betts has homered twice against him.
The Red Sox decided to start right-hander Hector Velázquez in Game 2. He’s 7-0 with a 2.64 ERA and 1.414 WHIP this season in 33 games (three starts).
Velázquez has made three appearances against the Orioles this season, including one start, and allowed two runs and nine hits with seven strikeouts in 8 1/3 innings. Adam Jones is 3-for-4 against him.
Jones is batting .353 (24-for-68) since the break.
The Orioles struck out 14 times in Game 1.
For the Orioles
Jace Peterson 2B
Jonathan Villar SS
Adam Jones CF
Trey Mancini 1B
Chris Davis DH
Renato Nuñez 3B
Cedric Mullins CF
Joey Rickard LF
Caleb Joseph C
Yefry Ramírez RHP
For the Red Sox
Mookie Betts RF
Brock Holt 2B
Steve Pearce 1B
J.D. Martinez LF
Xander Bogaerts SS
Rafael Devers 3B
Eduardo Núñez DH
Dan Butler C
Jackie Bradley Jr. CF
Hector Velázquez RHP
Update: Núñez’s RBI double with no outs in the second inning scored Mancini and gave the Orioles a 1-0 lead. But they stranded two runners in scoring position.
Update II: Mancini had an RBI single off Brandon Workman in the third inning and J.D. Martinez hit a solo home run off Ramírez in the fourth. The Orioles lead 2-1.
Update III: Eduardo Nuñez led off the fifth with a triple and scored on Dan Butler’s sacrifice fly to tie the game.