Denard Span is in the starting lineup for the first time since leaving Tuesday's game early with a scraped knee.

Span left in the third inning after making a diving catch to end the inning against the Mets. Ryan Zimmerman will get the start in left field with Bryce Harper moving over to right. Right-hander Doug Fister seeks his career-high 16th win of the season. With a win, the Nationals can clinch home-field advantage in the National League throughout the playoffs. For the Nationals CF Denard Span 3B Anthony Rendon LF Ryan Zimmerman 1B Adam LaRoche SS Ian Desmond RF Bryce Harper 2B Asdrubal Cabrera C Jose Lobaton RHP Doug Fister