Another five-run inning doomed the Orioles tonight.

Josh Naylor’s grand slam off reliever Anthony Nunez in the fifth capped a Mariners rally that pointed them toward a 6-3 win before an announced crowd of 12,377 at Camden Yards.

A third loss in a row has lowered the Orioles’ record to 31-36.

The Orioles loaded the bases against Emerson Hancock with one out in the third on a hit-by-pitch and back-to-back walks, and Pete Alonso flied to center field for a 1-0 lead.

The Mariners tied the game in the fifth on Ryan Bliss’ sacrifice fly off Trey Gibson after singles by Dominic Canzone and Jhonny Pereda. Three of the five hits that Gibson surrendered came in the fifth, and Nunez replaced him with two outs.

Julio Rodríguez walked and Naylor homered onto the flag court in right field, a 358-foot slam that gave Seattle a 5-1 lead.

“I wish that Nunez would have leaned on his strengths a little bit there,” said manager Craig Albernaz. “I’m not saying his fastball isn’t one of his strengths, but he has an elite changeup, you know, you’re ahead, and he has the sweeper as well. It’s not saying that it was a bad pitch by any stretch, but a changeup would’ve been awesome there.

“You can hindsight from the dugout on pitch calling, doing it as a catcher, like, I get it. And Nunez, like I said, the walk is the one that hurt him. To try to sneak the fastball there, I can see it, but also just Naylor got enough of it.”

Nunez retired seven in a row before Albert Suárez replaced him in the eighth and allowed a run on Randy Arozarena’s third single.

The Blue Jays overcame a 4-0 deficit yesterday with a five-run sixth. They scored four times in the third inning Saturday while breaking a 1-1 tie.

Orioles had chance to turn tables in seventh …

The Mariners began tonight with a 3.15 bullpen ERA that ranked as the second lowest in the majors, but it had some shaky moments.

Cooper Criswell began the seventh by walking Coby Mayo and giving up a single to Blaze Alexander. The runners advanced on Sam Huff’s slow roller near the mound, and Matt Brash entered the game.

Bat at your own risk.

The first pitch reached the backstop to score Mayo, and the second pitch – a 98.1 mph sinker – drilled Taylor Ward in the middle of the back. Gunnar Henderson walked to load the bases, but Brash escaped the jam by striking out Alonso and retiring Colton Cowser on a grounder.

Alonso got ahead 3-0 and appeared to walk with the count full, but the call was overturned on a timely challenge. He had to spin out of the box after a pitch came near his head.

… and again in eighth

Eduard Bazardo replaced Brash, the first two batters reached and Alexander singled with one out to cut the lead to 6-3.

Samuel Basallo pinch-hit for Huff with runners on the corners, bringing the crowd to its feet, and he flied 381 feet to center field. Jackson Holliday scored, but Rodríguez threw out Alexander at second base.

The Mariners challenged, and Alexander was ruled to have been tagged before Holliday’s foot touched the plate. Take the run off the board.

“Talked to Blaze the next inning,” Albernaz said. “I love the aggressiveness, but like I told Blaze, and him being an infielder, he knows the cutoff and how it gets aligned and configured, and first base is vacant by position, so there’s no one at first. So him tagging up and then running is the right play, but he has the ability to read the throw, and you can stop and just walk back to first, and that’s what we talked about.

“Once you see the throw on line, and we all know Julio can throw, like he’s a premium defender in center field, it surprised me that he kept going. But it’s one of those things, I love the aggressiveness. It’s just smart aggressiveness and knowing and reading the throw and getting back. And Holliday did an outstanding job of running hard through home.

“That was the first thing I looked at on the high home. He tagged up and he didn’t let up running hard through home. So Holliday did an outstanding job on that. It’s just, Blaze just has to read the throw and just get back to first.

“Yeah, that one hurt.”

Holliday was prepared for the possibility of the situation that unfolded.

“Buck (Britton) really did a good job,” Holliday said. “He was like, ‘Make sure you run hard through the base there.’ He kind of informed me, I guess. We made an aggressive play and they made a good throw.”

Opportunities lost

The Orioles went 1-for-9 with runners in scoring position and left 10 on base. Colton Cowser, batting cleanup for the first time this season, stranded seven over four of his at-bats.

“We know coming in with Seattle, pitching is their strength,” Albernaz said. “It always has been, and Emerson’s having a great year, throwing the ball extremely well. Their bullpen has always been a force. And so going into it, we knew we had to grind and really force them to work, and we did that. We just couldn’t come through with the big blow. But it’s one of those games where you’re proud of how they fought, because every opportunity, like we talked about pregame, our guys could have folded, but they kept on fighting and giving themselves an opportunity.

“It’s just that big knock that eluded us. We hit some balls hard and well that I was actually kind of surprised that they didn’t leave the yard.

Gibson given another chance

Brandon Young has taken full advantage of his latest opportunity in the rotation, and Trey Gibson wants to do the same.

The Orioles recalled Gibson earlier today and placed Chris Bassitt on the 15-day injured list with lower-back discomfort. Bassitt is weighing his options while the team seeks a second opinion, which seems to indicate that his return could be delayed.

Gibson made his fourth major league appearance and third start tonight, and he was charged with three runs in 4 2/3 innings. He walked one and didn’t record a strikeout, and Albernaz pulled him after 68 pitches.

“Gibson was falling behind guys,” Albernaz said. “The inning before he fell behind every single hitter he faced. He was giving up some loud contact as well. That inning where they tied the game up, it kept going, got to Julio, and I decided that we needed to stop the game there to give ourselves a chance.”

Gibson got away with some hard contact early. Rodríguez lined to right field at 105.5 mph in the first inning and Luke Raley lined to right at 102.8 in the second, in between Arozarena’s leadoff single and Canzone’s walk.

Alexander charged Pereda’s slow roller with two outs and made the throw on the run to strand two runners and complete a 21-pitch inning for Gibson. Alonso scooped the ball out of the dirt.

Gibson retired the side in order in the third on 12 pitches, inducing three ground balls. Arozarena singled again in the fourth and Gibson picked him off first base.

Naylor’s homer off Nunez raised Gibson’s ERA to 4.24. Gibson has struck out only five batters in 17 innings.

Every game is a learning experience for the rookie. Asked what he can take away from tonight’s start, he said, “Just keep pounding the zone. One of the biggest things I feel like I’ve seen about myself or learned about myself since coming up to the bigs is just kinda getting ahead to two strikes. I’m the type of pitcher that likes to pitch to ground balls and I feel like I did a decent job of getting those tonight.”

Typical Taylor Ward at-bat

Ward stayed in the leadoff spot tonight and worked Hancock for eight pitches in the first inning.

With the count full, Ward lined a single into left field at 108.2 mph. He was down 0-2 in the count and fouled off a sweeper at 1-2 and a 96 mph fastball at 2-2 before pulling a sinker past third baseman Patrick Wisdom.

Ward got ahead 3-0 in the third inning, took a sinker for a strike and drew his 57th walk.

Known for his patience at the plate, Ward also can become more aggressive and go after the first pitch, which he did in the fifth inning with a two-out single at 106.4 mph. And he reached base a fourth time in the seventh, but it came with a bruise.

Ward slugged his third home run Sunday afternoon in Toronto. He’s still homerless at Camden Yards since the Orioles traded for him.